Compound Q&A
How is 5-Amino-2-fluorophenylboronic acid (CAS: 873566-74-6) typically synthesized?
Answer
5-Amino-2-fluorophenylboronic acid is typically synthesized through a multistep procedure involving the protection of a phenol, followed by a substitution reaction with a boronic acid derivative. Common reagents include boronic acids, catalysts like palladium(II) acetate and triphenylphosphine, and a base such as triethylamine. The yield is generally around 70-80%.
About
CAS No
873566-74-6
English Name
5-Amino-2-fluorophenylboronic acid
Molecular Formula
C6H7BFNO2
Molecular Weight
154.94 g/mol
SMILES
B(C1=C(C=CC(=C1)N)F)(O)O
InChIKey
CDZMVORRMKESPD-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29
