How is N-{5-[(4-{[5-Chloro-4-fluoro-2-(2-hydroxy-2-propanyl)phenyl]amino}-2-pyrimidinyl)amino]-2-[(3S)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl}acrylamide (CAS: 2370013-49-1) typically synthesized?

This compound is synthesized via a multistep process involving the coupling of an amino pyrimidine derivative with a pyrrolidine-containing methoxyphenyl acrylamide. The synthesis typically requires mild to moderate conditions, with the use of catalysts such as EDC and HOBt, and provides good to excellent yields. The process involves protecting groups and careful control of reaction conditions to ensure high selectivity and purity.