Compound Q&A

What are the physical and chemical properties of N-{5-[(4-{[5-Chloro-4-fluoro-2-(2-hydroxy-2-propanyl)phenyl]amino}-2-pyrimidinyl)amino]-2-[(3S)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl}acrylamide (CAS: 2370013-49-1)?

Answer

N-{5-[(4-{[5-Chloro-4-fluoro-2-(2-hydroxy-2-propanyl)phenyl]amino}-2-pyrimidinyl)amino]-2-[(3S)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl}acrylamide
This compound is a crystalline solid with a molecular weight of approximately 660.5 g/mol. It has low water solubility and moderate solubility in organic solvents like DMSO. The compound is reactive, particularly towards nucleophiles and reducing agents, and may undergo hydrolysis under basic conditions. It is stable under normal storage conditions but requires protection from moisture and light.

About

English Name N-{5-[(4-{[5-Chloro-4-fluoro-2-(2-hydroxy-2-propanyl)phenyl]amino}-2-pyrimidinyl)amino]-2-[(3S)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl}acrylamide
Molecular Formula C29H35ClFN7O3
Molecular Weight 584.1 g/mol
SMILES CN(C)[C@@H]1CN(CC1)C1C=C(OC)C(=CC=1NC(=O)C=C)NC1N=C(C=CN=1)NC1C=C(Cl)C(F)=CC=1C(C)(C)O
InChIKey BTMKEDDEMKKSEF-KRWDZBQOSA-N
Last Updated: 2025-11-27 23:35

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