Compound Q&A

How is Ethyl 6-chloropyridazine-4-carboxylate (CAS: 612834-90-9) typically synthesized?

Answer

Ethyl 6-chloropyridazine-4-carboxylate
Ethyl 6-chloropyridazine-4-carboxylate is commonly synthesized by reacting 4-chloropyridazine with acetyl chloride in the presence of an acid catalyst, such as phosphoric acid. This reaction is carried out at room temperature, and the product is purified by recrystallization from a suitable solvent. The yield is typically around 75-80%, with good selectivity and reactivity.

About

English Name Ethyl 6-chloropyridazine-4-carboxylate
Molecular Formula C7H7ClN2O2
Molecular Weight 186.6 g/mol
SMILES CCOC(=O)C1=CC(=NN=C1)Cl
InChIKey DZSYDSVXAOQGNB-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31

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