Compound Q&A
Are there alternatives to Ac-VDVAD-pNA (CAS: 189688-53-5) in synthesis?
Answer
For synthesizing similar functions, alternatives to Ac-VDVAD-pNA (CAS: 189688-53-5) include other fluorometric substrates like Ac-DEVD-pNA and Ac-LEHD-pNA, which are commonly used for caspase activity assays. These alternatives offer similar enzymatic cleavage properties but may have different specificities and substrate affinities. Researchers often choose based on the specific caspase isoform they are studying and the experimental requirements.
About
CAS No
189684-53-5
English Name
Ac-VDVAD-pNA
Molecular Formula
C29H41N7O12
Molecular Weight
679.7 g/mol
SMILES
CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C
InChIKey
SIOKOOKURWWOID-UHFFFAOYSA-N
Last Updated: 2025-11-14 19:17
