How is Methyl 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS: 363185-87-9) typically synthesized?

Methyl 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is typically synthesized via a multistep process involving the formation of an aryl boronic acid derivative followed by its coupling with a carboxylic acid. This reaction is catalyzed by palladium and often involves the use of a base like potassium carbonate. The overall yield is moderate to good, with high selectivity for the desired product.