Compound Q&A
How is 2-Phenyl-1-(1-piperazinyl)ethanone (CAS: 88372-33-2) typically synthesized?
Answer
2-Phenyl-1-(1-piperazinyl)ethanone is commonly synthesized via the condensation of 2-phenylethylenecarbodiimide with 1-piperazinecarboxylic acid. This reaction typically involves the use of a catalyst such as 4-dimethylaminopyridine to enhance the yield. The product is obtained with good selectivity and a yield of around 70-80%.
About
CAS No
88372-33-2
English Name
2-Phenyl-1-(1-piperazinyl)ethanone
Molecular Formula
C12H16N2O
Molecular Weight
204.27299999999994 g/mol
SMILES
C1CN(CCN1)C(=O)CC2=CC=CC=C2
InChIKey
ZIZWHGCVLFSQBP-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01
