Compound Q&A

How is 6-Aminonicotinaldehyde hydrochloride (CAS: 1588441-31-9) typically synthesized?

Answer

6-Aminonicotinaldehyde hydrochloride (1:1)
6-Aminonicotinaldehyde hydrochloride is typically synthesized by the condensation of 6-aminonicotinic acid and formaldehyde in the presence of a strong acid catalyst such as hydrochloric acid. The reaction is conducted at room temperature and yields a high percentage of the desired product with good selectivity. The yield is around 90%.

About

English Name 6-Aminonicotinaldehyde hydrochloride (1:1)
Molecular Formula C6H7ClN2O
Molecular Weight 158.588 g/mol
SMILES Cl.Nc1ccc(C=O)cn1
InChIKey HWMXZDKTFAIWET-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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