Compound Q&A
How is 2-Chloro-3-methylbenzonitrile (CAS: 15013-71-5) typically synthesized?
Answer
2-Chloro-3-methylbenzonitrile is typically synthesized via the reaction of chloromethylbenzene with sodium cyanide in an aprotic solvent like dimethylformamide (DMF) under basic conditions. The reaction is exothermic and requires careful temperature control to achieve high yields and selectivity. The process is catalyzed by a base such as potassium carbonate.
About
CAS No
15013-71-5
English Name
2-Chloro-3-methylbenzonitrile
Molecular Formula
C8H6ClN
Molecular Weight
140.61 g/mol
SMILES
CC1=C(C(=CC=C1)C#N)Cl
InChIKey
RBHUDDGPJRWBTF-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01
