Compound Q&A
How is O-Methyl Atorvastatin Calcium Salt (CAS: 887196-29-4) typically synthesized?
Answer
O-Methyl Atorvastatin Calcium Salt (CAS: 887196-29-4) is typically synthesized through a multi-step process involving the key intermediate atorvastatin, which is then methylated and converted to the calcium salt. Common catalysts include aluminum chloride, and the reaction conditions are optimized for high yield and selectivity. The process involves protection of functional groups to ensure desired regioselectivity.
About
CAS No
887196-29-4
English Name
O-Methyl Atorvastatin Calcium Salt
Molecular Formula
C68H72CaF2N4O10
Molecular Weight
611.75 g/mol
SMILES
CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])OC)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])OC)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]
InChIKey
WSJYEDNFTDTVCI-GWQGKXOTSA-L
Last Updated: 2025-11-07 15:33
