Compound Q&A
How is 5-(Difluoromethyl)-1,3,4-thiadiazol-2-amine (CAS: 25306-15-4) typically synthesized?
Answer
5-(Difluoromethyl)-1,3,4-thiadiazol-2-amine is commonly synthesized via amidation of 5-(dichloromethyl)-1,3,4-thiadiazole with an amine such as methylamine. The reaction is conducted under mild conditions, and the yield is typically good. Various solvents can be used, and the reaction is often carried out in the presence of a base like sodium hydroxide to enhance the reaction rate and selectivity.
About
CAS No
25306-15-4
English Name
5-(Difluoromethyl)-1,3,4-thiadiazol-2-amine
Molecular Formula
C3H3F2N3S
Molecular Weight
151.14 g/mol
SMILES
FC(c1nnc(s1)N)F
InChIKey
NBGMELMIAOKZSD-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33
