Compound Q&A

How is 2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone (CAS: 80466-56-4) typically synthesized?

Answer

2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone
2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone can be synthesized through the nitration of 2-hydroxy-5-nitropyrimidine followed by reduction of the nitro group to an amino group. Commonly used conditions include the use of nitric acid in the presence of sulfuric acid as a catalyst, and subsequent hydrogenation to achieve the desired amino functionality.

About

CAS No 80466-56-4
English Name 2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone
Molecular Formula C4H4N4O4
Molecular Weight 172.1 g/mol
SMILES C1(=C(N=C(NC1=O)N)O)[N+](=O)[O-]
InChIKey ZEBYRLPUWQNZNY-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33

Related Q&A

Compound Q&A

What are the physical and chemical properties of 2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone (CAS: 80466-56-4)?

2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone is a crystalline solid with a molecular weight of appro...

Compound Q&A

What industries use 2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone (CAS: 80466-56-4)?

2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone finds applications in the pharmaceutical industry as a ...

Compound Q&A

What precautions should be taken when handling 2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone (CAS: 80466-56-4)?

When handling 2-Amino-6-hydroxy-5-nitro-4(1H)-pyrimidinone, it is essential to wear protective equip...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...