Compound Q&A
How is 2-Methyl-5-nitro-2H-indazole (CAS: 5228-48-8) typically synthesized?
Answer
2-Methyl-5-nitro-2H-indazole can be synthesized via the nitration of 2-methylindazole using nitric acid and sulfuric acid as the nitrating agent. The reaction is carried out in an aqueous phase under controlled temperature conditions to achieve a yield of around 70-80%. Further purification is often required to obtain the high-purity compound.
About
CAS No
5228-48-8
English Name
2-Methyl-5-nitro-2H-indazole
Molecular Formula
C8H7N3O2
Molecular Weight
177.16 g/mol
SMILES
CN1C=C2C=C(C=CC2=N1)[N+](=O)[O-]
InChIKey
IWPBWVZEOVCZRX-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33
