Compound Q&A

How is 3-Methoxy-5-methylpyrazin-2-amine (CAS: 89464-87-9) typically synthesized?

Answer

3-Methoxy-5-methylpyrazin-2-amine
3-Methoxy-5-methylpyrazin-2-amine is typically synthesized via a multistep process. The first step involves the condensation of methylpyrazine with methoxyamine hydrochloride using a basic catalyst like sodium hydroxide. This step is followed by the reduction of the resulting N-oxime using sodium borohydride. The overall yield is around 75%, and the reaction is selective, producing the desired amine with high purity.

About

CAS No 89464-87-9
English Name 3-Methoxy-5-methylpyrazin-2-amine
Molecular Formula C6H9N3O
Molecular Weight 139.16 g/mol
SMILES CC1=CN=C(C(=N1)OC)N
InChIKey NIQNPTQRAGJGPS-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11

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