Compound Q&A

How is 1H-Imidazole-4-sulfonyl chloride (CAS: 58767-51-4) typically synthesized?

Answer

1H-Imidazole-4-sulfonyl chloride
1H-Imidazole-4-sulfonyl chloride is commonly synthesized via the reaction of 4-(chlorosulfonyl)benzenesulfonamide with imidazole in the presence of a base like sodium hydride or potassium carbonate. The yield is typically around 80%, and the method involves careful control of the reaction conditions to achieve high selectivity and purity.

About

CAS No 58767-51-4
English Name 1H-Imidazole-4-sulfonyl chloride
Molecular Formula C3H3ClN2O2S
Molecular Weight 166.59 g/mol
SMILES ClS(=O)(=O)c1c[nH]cn1
InChIKey MXCZCMCHRWGSBX-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11

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