Compound Q&A

How is 2-(4-Methylphenyl)-1,3-benzoxazole (CAS: 835-71-2) typically synthesized?

Answer

2-(4-Methylphenyl)-1,3-benzoxazole
2-(4-Methylphenyl)-1,3-benzoxazole (CAS: 835-71-2) is typically synthesized via a multistep synthesis involving the protection of a primary amine with a benzyl group, followed by coupling with a substituted aromatic compound to form the benzoxazole ring. Palladium catalysis is often used, and the reaction is carried out under mild conditions to achieve high yields and good selectivity.

About

CAS No 835-71-2
English Name 2-(4-Methylphenyl)-1,3-benzoxazole
Molecular Formula C14H11NO
Molecular Weight 209.25 g/mol
SMILES CC1=CC=C(C=C1)C2=NC3=CC=CC=C3O2
InChIKey UTMZWCTVPHAOJZ-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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