2-(4-Methylphenyl)-1,3-benzoxazole(CAS: 835-71-2)

2-(4-Methylphenyl)-1,3-benzoxazole (CAS: 835-71-2) is a crystalline solid with a molecular weight of approximately 228.23 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. The compound is relatively stable under normal conditions but can undergo mild hydrolysis in basic media. It does not readily react with common reagents but may show reactivity in strong oxidizing or reducing environments.

2-(4-Methylphenyl)-1,3-benzoxazole (CAS: 835-71-2) is typically synthesized via a multistep synthesis involving the protection of a primary amine with a benzyl group, followed by coupling with a substituted aromatic compound to form the benzoxazole ring. Palladium catalysis is often used, and the reaction is carried out under mild conditions to achieve high yields and good selectivity.

2-(4-Methylphenyl)-1,3-benzoxazole (CAS: 835-71-2) is used in various industries, including pharmaceuticals, where it serves as a precursor for drug intermediates, and in the polymer industry, where it can enhance the thermal stability of polymers. It is also utilized in the manufacture of sensors and semiconductors due to its electronic properties.

When handling 2-(4-Methylphenyl)-1,3-benzoxazole (CAS: 835-71-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up promptly using suitable materials, and it is advisable to refer to the Material Safety Data Sheet (MSDS) for specific guidelines and emergency procedures.