Compound Q&A

How is 4-Bromo-3-fluoro-5-methylaniline (CAS: 1356113-07-9) typically synthesized?

Answer

4-Bromo-3-fluoro-5-methylaniline
4-Bromo-3-fluoro-5-methylaniline (CAS: 1356113-07-9) can be synthesized via a series of steps including bromination and methylation of 3-fluoro-5-methylaniline. Commonly, the reactant is brominated using N-bromosuccinimide (NBS) and benzoyl peroxide under UV light, followed by treatment with methyl iodide in the presence of pyridine. The overall yield is moderate, and selectivity is good.

About

English Name 4-Bromo-3-fluoro-5-methylaniline
Molecular Formula C7H7BrFN
Molecular Weight 204.042 g/mol
SMILES CC1=CC(=CC(=C1Br)F)N
InChIKey WTNCRDVVJCQOOF-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29

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