Compound Q&A
How is [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid benzenesulfonate (CAS: 1138245-21-2) typically synthesized?
Answer
![[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid benzenesulfonate (1:1)](https://static.chemtradehub.com/structs/113/1138245-21-2-5a7d.webp "[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid benzenesulfonate (1:1)")
This compound is typically synthesized via a multi-step process involving the condensation of an ethyl bicycloheptene derivative with benzenesulfonyl chloride followed by the addition of an amine. The synthesis involves the use of Lewis acids as catalysts, and the product is isolated by crystallization. The process requires careful control of reaction temperature and pH to achieve high yields and selectivity.
About
CAS No
1138245-21-2
English Name
[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid benzenesulfonate (1:1)
Molecular Formula
C18H25NO5S
Molecular Weight
367.47 g/mol
SMILES
CCC1=C[C@@H]2[C@H](C1)C[C@@]2(CC(=O)O)CN.c1ccc(cc1)S(=O)(=O)O
InChIKey
OKJXJRVWXYRSAN-TXULWXBWSA-N
Last Updated: 2025-11-04 22:31
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