Compound Q&A

How is 2,5-dioxopyrrolidin-1-yl 2-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate (CAS: 96735-88-5) typically synthesized?

Answer

2,5-dioxopyrrolidin-1-yl 2-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate
2,5-dioxopyrrolidin-1-yl 2-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate is typically synthesized via a multistep process involving condensation of a chromone derivative with a dioxopyrrolidine followed by acetylation. Common catalysts include Lewis acids like aluminum chloride. The yield is generally around 80%, and the reaction is conducted under anhydrous conditions to avoid unwanted side reactions.

About

CAS No 96735-88-5
English Name 2,5-dioxopyrrolidin-1-yl 2-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate
Molecular Formula C16H13NO7
Molecular Weight 331.28 g/mol
SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)O)CC(=O)ON3C(=O)CCC3=O
InChIKey VODLZKHEKKGCBG-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04

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