Compound Q&A
How is (1R)-1-[2-(Trifluoromethyl)phenyl]ethanamine (CAS: 127733-46-4) typically synthesized?
Answer
![(1R)-1-[2-(Trifluoromethyl)phenyl]ethanamine](https://static.chemtradehub.com/structs/127/127733-46-4-1a07.webp "(1R)-1-[2-(Trifluoromethyl)phenyl]ethanamine")
This compound is usually synthesized via amination of 2-(trifluoromethyl)benzaldehyde with ethylamine, using a catalytic amount of a suitable amine such as triethylamine. The reaction is typically carried out under mild conditions, leading to a high yield of the desired (1R)-isomer.
About
CAS No
127733-46-4
English Name
(1R)-1-[2-(Trifluoromethyl)phenyl]ethanamine
Molecular Formula
C9H10F3N
Molecular Weight
189.18 g/mol
SMILES
CC(C1=CC=CC=C1C(F)(F)F)N
InChIKey
DPLIMKBGTYIUCB-ZCFIWIBFSA-N
Last Updated: 2025-11-04 13:04
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