Compound Q&A

How is 5-Bromo-1-benzothiophene-3-carboxylic acid (CAS: 7312-24-5) typically synthesized?

Answer

5-Bromo-1-benzothiophene-3-carboxylic acid
5-Bromo-1-benzothiophene-3-carboxylic acid is commonly synthesized via bromination of 1-benzothiophene-3-carboxylic acid using N-bromosuccinimide (NBS) in the presence of a suitable catalyst such as benzoyl peroxide. The reaction is typically carried out under mild conditions, and the yield is moderate to good, depending on the purification method chosen.

About

CAS No 7312-24-5
English Name 5-Bromo-1-benzothiophene-3-carboxylic acid
Molecular Formula C9H5BrO2S
Molecular Weight 257.11 g/mol
SMILES C1=CC2=C(C=C1Br)C(=CS2)C(=O)O
InChIKey DWQBOPASRUUSKR-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04

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