Compound Q&A
How is 2,6-Dichloroimidazo[1,2-b]pyridazine (CAS: 112581-77-8) typically synthesized?
Answer
![2,6-Dichloroimidazo[1,2-b]pyridazine](https://static.chemtradehub.com/structs/112/112581-77-8-6408.webp "2,6-Dichloroimidazo[1,2-b]pyridazine")
2,6-Dichloroimidazo[1,2-b]pyridazine is usually synthesized via a multi-step process starting from chloropyridine and imidazole. The synthesis involves condensation reactions followed by chlorination steps. Commonly used catalysts include hydrogen chloride and thionyl chloride. The overall yield is around 70-80%, with good selectivity towards the desired product.
About
CAS No
112581-77-8
English Name
2,6-Dichloroimidazo[1,2-b]pyridazine
Molecular Formula
C6H3Cl2N3
Molecular Weight
188.02 g/mol
SMILES
C1=CC(=NN2C1=NC(=C2)Cl)Cl
InChIKey
MGNCSIAIZSTMHX-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12
![2,6-Dichloroimidazo[1,2-b]pyridazine — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}
![2,6-Dichloroimidazo[1,2-b]pyridazine — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![2,6-Dichloroimidazo[1,2-b]pyridazine — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}