Compound Q&A
How is Amylin (8-37) (human) (CAS: 135702-23-7) typically synthesized?
Answer
Amylin (8-37) (human) (CAS: 135702-23-7) is synthesized through solid-phase peptide synthesis (SPPS). The process involves sequential coupling of amino acids, using Fmoc chemistry and HBTU coupling reagent. The peptide is then cleaved from the resin using trifluoroacetic acid (TFA) and subsequent purification is achieved through HPLC. The synthesis typically yields a purity of over 95%, with excellent regioselectivity and good yield.
About
CAS No
135702-23-7
English Name
Amylin (8-37) (human)
Molecular Formula
C138H216N42O45
Molecular Weight
3183.4 g/mol
SMILES
CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N)NC(=O)C(C)NC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC3=CNC=N3)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)O)NC(=O)C(C)N
InChIKey
OBFZUAVBRVNJDZ-AWNVCVQVSA-N
Last Updated: 2025-11-01 22:12
