Compound Q&A
How is 3-Hydroxy-N-(2-naphthyl)-2-naphthamide (CAS: 135-64-8) typically synthesized?
Answer
3-Hydroxy-N-(2-naphthyl)-2-naphthamide (CAS: 135-64-8) is typically synthesized via an amide coupling reaction of 2-naphthylamine and 3-hydroxynaphthaldehyde. The reaction is often catalyzed by a Lewis acid such as aluminum trichloride and proceeds under reflux. The yield is moderate, around 50-60%, and the product can be purified by recrystallization from water or an organic solvent.
About
CAS No
135-64-8
English Name
3-Hydroxy-N-(2-naphthyl)-2-naphthamide
Molecular Formula
C21H15NO2
Molecular Weight
313.36 g/mol
SMILES
C1=CC=C2C=C(C=CC2=C1)NC(=O)C3=CC4=CC=CC=C4C=C3O
InChIKey
PMYDPQQPEAYXKD-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12
