Compound Q&A
How is 1-(4-Pyridinyl)-4-piperidinone (CAS: 126832-81-3) typically synthesized?
Answer
1-(4-Pyridinyl)-4-piperidinone is synthesized via the condensation of 4-piperidone and 4-pyridylamine. Commonly, this is achieved by reacting piperidone with 4-pyridylamine in the presence of a base such as triethylamine. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is around 85%, with good selectivity towards the desired product.
About
CAS No
126832-81-3
English Name
1-(4-Pyridinyl)-4-piperidinone
Molecular Formula
C10H12N2O
Molecular Weight
176.22 g/mol
SMILES
C1CN(CCC1=O)C2=CC=NC=C2
InChIKey
MAXMUBIIZUKOJF-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
