Compound Q&A

How is N-Methoxy-N-methyl-1H-indazole-3-carboxamide (CAS: 351457-12-0) typically synthesized?

Answer

N-Methoxy-N-methyl-1H-indazole-3-carboxamide
N-Methoxy-N-methyl-1H-indazole-3-carboxamide (CAS: 351457-12-0) can be synthesized by reacting 1-methyl-3-indolylamine with methoxyacetyl chloride in the presence of a base like triethylamine. The reaction yields the desired compound with good selectivity and a yield of around 85%. This method is widely used in the literature for the preparation of indazole derivatives.

About

English Name N-Methoxy-N-methyl-1H-indazole-3-carboxamide
Molecular Formula C10H11N3O2
Molecular Weight 205.22 g/mol
SMILES CN(C(=O)C1=NNC2=CC=CC=C21)OC
InChIKey NRQALXRUZKPBKP-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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