Compound Q&A

How is 1,4-Dimethyl-1H-pyrazole-3-carboxylic acid (CAS: 89202-89-1) typically synthesized?

Answer

1,4-Dimethyl-1H-pyrazole-3-carboxylic acid
1,4-Dimethyl-1H-pyrazole-3-carboxylic acid is synthesized through a multistep process involving the reaction of 1,4-dimethylpyrazole with carboxylic anhydride or a carboxylic acid under appropriate conditions. Commonly, this involves the condensation of 1,4-dimethylpyrazole with acetic anhydride in the presence of a catalyst like p-toluenesulfonic acid. The yield is typically around 85-90%, and the product is purified by recrystallization from ethanol.

About

CAS No 89202-89-1
English Name 1,4-Dimethyl-1H-pyrazole-3-carboxylic acid
Molecular Formula C6H8N2O2
Molecular Weight 140.14 g/mol
SMILES CC1=CN(N=C1C(=O)O)C
InChIKey WYCQFCGAORZRDX-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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