Compound Q&A
How is (3R,4R,5R)-5-[(Benzoyloxy)methyl]-3-methyl-2-oxotetrahydrofuran-3,4-diyl dibenzoate (CAS: 7392-74-7) typically synthesized?
Answer
![(3R,4R,5R)-5-[(Benzoyloxy)methyl]-3-methyl-2-oxotetrahydrofuran-3,4-diyl dibenzoate](https://static.chemtradehub.com/structs/739/7392-74-7-e2df.webp "(3R,4R,5R)-5-[(Benzoyloxy)methyl]-3-methyl-2-oxotetrahydrofuran-3,4-diyl dibenzoate")
(3R,4R,5R)-5-[(Benzoyloxy)methyl]-3-methyl-2-oxotetrahydrofuran-3,4-diyl dibenzoate (CAS: 7392-74-7) can be synthesized via a multi-step process, starting from the diol and benzoyl chloride. The key steps involve esterification, ring closure, and benzoate formation. Common solvents used include dichloromethane, and the reaction is typically catalyzed by a Lewis acid like aluminum chloride. The overall yield is moderate, around 60-70%, with high selectivity for the desired product.
About
CAS No
7392-74-7
English Name
(3R,4R,5R)-5-[(Benzoyloxy)methyl]-3-methyl-2-oxotetrahydrofuran-3,4-diyl dibenzoate
Molecular Formula
C27H22O8
Molecular Weight
474.47 g/mol
SMILES
CC1(C(C(OC1=O)COC(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)OC(=O)C4=CC=CC=C4
InChIKey
KOELERLPRQKGLG-VHFRWLAGSA-N
Last Updated: 2025-11-01 18:55
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