Compound Q&A

How is (5-Bromo-2-chloro-3-pyridinyl)methanol (CAS: 742100-75-0) typically synthesized?

Answer

(5-Bromo-2-chloro-3-pyridinyl)methanol
(5-Bromo-2-chloro-3-pyridinyl)methanol can be synthesized using a multi-step process involving bromination of 3-chloropyridine followed by methylation. The reaction involves the use of bromine and methyl halides as reagents, with catalysis by Lewis acids like aluminum trichloride. The yield and selectivity can be optimized through careful control of reaction conditions.

About

English Name (5-Bromo-2-chloro-3-pyridinyl)methanol
Molecular Formula C6H5BrClNO
Molecular Weight 222.47 g/mol
SMILES C1=C(C=NC(=C1CO)Cl)Br
InChIKey ZZGSPGXWLOYKFH-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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