Compound Q&A
How is 3-Bromo-1-(phenylsulfonyl)-1H-indole (CAS: 99655-68-2) typically synthesized?
Answer
3-Bromo-1-(phenylsulfonyl)-1H-indole is typically synthesized via a multi-step process. The first step involves the bromination of indole, followed by the coupling with phenylsulfonyl chloride in the presence of a base. Commonly used catalysts include pyridine and 4-dimethylaminopyridine (DMAP). The yield of the final product can be around 70-80%, with good selectivity towards the desired product.
About
CAS No
99655-68-2
English Name
3-Bromo-1-(phenylsulfonyl)-1H-indole
Molecular Formula
C14H10BrNO2S
Molecular Weight
336.21 g/mol
SMILES
C1=CC=C(C=C1)S(=O)(=O)N2C=C(C3=CC=CC=C32)Br
InChIKey
MXPFKHHDXIJNDX-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
