Compound Q&A
How is Methyl 3-amino-6-iodo-2-pyrazinecarboxylate (CAS: 1458-16-8) typically synthesized?
Answer
Methyl 3-amino-6-iodo-2-pyrazinecarboxylate (CAS: 1458-16-8) is typically synthesized via the condensation of methyl 3-amino-2-pyrazinecarboxylate with iodine in the presence of a base such as sodium hydride. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is generally 75-80%.
About
CAS No
1458-16-8
English Name
Methyl 3-amino-6-iodo-2-pyrazinecarboxylate
Molecular Formula
C6H6IN3O2
Molecular Weight
279.04 g/mol
SMILES
COC(=O)C1=NC(=CN=C1N)I
InChIKey
FDLARAKNPMCCKJ-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
