Methyl 3-amino-6-iodo-2-pyrazinecarboxylate(CAS: 1458-16-8)

Methyl 3-amino-6-iodo-2-pyrazinecarboxylate (CAS: 1458-16-8) is crystalline at room temperature. Its molecular weight is approximately 313.03 g/mol. The compound is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It is moderately reactive towards nucleophiles and can undergo substitution reactions.

Methyl 3-amino-6-iodo-2-pyrazinecarboxylate (CAS: 1458-16-8) is typically synthesized via the condensation of methyl 3-amino-2-pyrazinecarboxylate with iodine in the presence of a base such as sodium hydride. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is generally 75-80%.

Methyl 3-amino-6-iodo-2-pyrazinecarboxylate (CAS: 1458-16-8) is used in the pharmaceutical and chemical industries for intermediate synthesis and potentially in the development of new drugs. It may also have applications in the polymer industry for specific additive formulations.

When handling Methyl 3-amino-6-iodo-2-pyrazinecarboxylate (CAS: 1458-16-8), wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a fume hood. Store the compound in a cool, dry place away from direct sunlight. In case of spill, contact a supervisor and follow proper waste disposal procedures. Refer to the safety data sheet (SDS) for detailed information.