Compound Q&A

How is 2-(4-Aminophenyl)-N-methylethanesulfonamide (CAS: 98623-16-6) typically synthesized?

Answer

2-(4-Aminophenyl)-N-methylethanesulfonamide
2-(4-Aminophenyl)-N-methylethanesulfonamide (CAS: 98623-16-6) can be synthesized via a multistep process involving the reaction of 4-aminophenol with methanesulfonyl chloride in the presence of a base like sodium hydroxide. The key steps include the formation of the methanesulfonate ester followed by the reduction of the nitro group to an amine. The yield is typically around 70-80%, and the method requires appropriate handling of reagents and solvents.

About

CAS No 98623-16-6
English Name 2-(4-Aminophenyl)-N-methylethanesulfonamide
Molecular Formula C9H14N2O2S
Molecular Weight 214.29 g/mol
SMILES CNS(=O)(=O)CCC1=CC=C(C=C1)N
InChIKey SDXLSPCIRDEJKT-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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