Compound Q&A
How is 5-((tert-Butoxycarbonyl)amino)pyrazine-2-carboxylic acid (CAS: 891782-63-1) typically synthesized?
Answer
5-((tert-Butoxycarbonyl)amino)pyrazine-2-carboxylic acid is commonly synthesized via the condensation of 5-amino-2-pyrazinecarboxylic acid with tert-butoxycarbonyl chloride in the presence of a base like triethylamine. The reaction typically provides good yield (70-80%) and can be performed in dimethylformamide (DMF) as a solvent. The synthesis involves careful control of reaction conditions to achieve the desired regioisomer.
About
CAS No
891782-63-1
English Name
5-((tert-Butoxycarbonyl)amino)pyrazine-2-carboxylic acid
Molecular Formula
C10H13N3O4
Molecular Weight
239.23 g/mol
SMILES
CC(C)(C)OC(=O)NC1=NC=C(N=C1)C(=O)O
InChIKey
MOLNWRVQKCBISZ-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
