Compound Q&A
How is (1S)-1-(2-Methoxyphenyl)ethanamine (CAS: 68285-24-5) typically synthesized?
Answer
(1S)-1-(2-Methoxyphenyl)ethanamine can be synthesized via aminomethylation of 2-methoxybenzene using water as the amine source. The reaction is typically conducted in the presence of a catalytic amount of a strong acid like sulfuric acid or hydrochloric acid. The yield is around 85-90%, with good selectivity to the (S)-enantiomer.
About
CAS No
68285-24-5
English Name
(1S)-1-(2-Methoxyphenyl)ethanamine
Molecular Formula
C9H13NO
Molecular Weight
151.21 g/mol
SMILES
CC(C1=CC=CC=C1OC)N
InChIKey
VENQOHAPVLVQKV-ZETCQYMHSA-N
Last Updated: 2025-11-01 12:59
