Compound Q&A
How is 3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate (CAS: 886-74-8) typically synthesized?
Answer
3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate (CAS: 886-74-8) is typically synthesized by the reaction of 4-chlorophenol with 2-hydroxypropyl carbamate. The process involves the condensation of 4-chlorophenol with 2-hydroxypropyl isocyanate in the presence of a suitable base such as potassium carbonate. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is usually around 70-80%, and the product is isolated by filtration and recrystallization.
About
CAS No
886-74-8
English Name
3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate
Molecular Formula
C10H12ClNO4
Molecular Weight
245.66 g/mol
SMILES
C1=CC(=CC=C1OCC(COC(=O)N)O)Cl
InChIKey
SKPLBLUECSEIFO-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
