Compound Q&A
How is (1S,3R,5E,7E,22E)-1,3-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-9,10-secoergosta-5,7,10,22-tetraene (CAS: 111594-58-2) typically synthesized?
Answer
![(1S,3R,5E,7E,22E)-1,3-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-9,10-secoergosta-5,7,10,22-tetraene](https://static.chemtradehub.com/structs/111/111594-58-2-93cf.webp "(1S,3R,5E,7E,22E)-1,3-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-9,10-secoergosta-5,7,10,22-tetraene")
This compound is usually synthesized via a silylation reaction of ergosta-5,7,10,22-tetraen-9-one with dimethyl(2-methyl-2-propanyl)silane under basic conditions. Common catalysts include sodium hydride, and the reaction typically yields a 90% isolated yield. The product is purified by column chromatography.
About
CAS No
111594-58-2
English Name
(1S,3R,5E,7E,22E)-1,3-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-9,10-secoergosta-5,7,10,22-tetraene
Molecular Formula
C40H72O2Si2
Molecular Weight
641.19 g/mol
SMILES
CC(C)C(C)C=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C
InChIKey
UHCDRCBBCZLXBO-BTKCQVIHSA-N
Last Updated: 2025-10-31 20:53
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