Compound Q&A
How is 2-(4-Morpholinyl)-5-(trifluoromethyl)aniline (CAS: 784-57-6) typically synthesized?
Answer
2-(4-Morpholinyl)-5-(trifluoromethyl)aniline (CAS: 784-57-6) is commonly synthesized via the Friedel-Crafts alkylation of 4-morpholinylaniline with trifluoromethylating agents like trifluoromethyl sulfonyl chloride in the presence of a Lewis acid catalyst. The reaction yields a high selectivity and good yield, making it a reliable method for industrial production. Detailed procedures are available in the literature and textbooks.
About
CAS No
784-57-6
English Name
2-(4-Morpholinyl)-5-(trifluoromethyl)aniline
Molecular Formula
C11H13F3N2O
Molecular Weight
246.23 g/mol
SMILES
C1COCCN1C2=C(C=C(C=C2)C(F)(F)F)N
InChIKey
CNVOJNRNRNAOOP-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
