Compound Q&A
How is 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea (CAS: 1430213-30-1) typically synthesized?
Answer
This compound is typically synthesized via a multi-step process involving the coupling of 4-fluoro-3-(trifluoromethyl)benzaldehyde, 5-(pyridin-4-yl)-1,3,4-thiadiazole, and urea. The process includes protection and deprotection steps, utilizing catalysts like palladium and amines. The yield is generally good, and the final product is purified by recrystallization or column chromatography.
About
CAS No
1430213-30-1
English Name
1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea
Molecular Formula
C15H9F4N5OS
Molecular Weight
383.33 g/mol
SMILES
C1=CC(=C(C=C1NC(=O)NC2=NN=C(S2)C3=CC=NC=C3)C(F)(F)F)F
InChIKey
WMCOYUSJXXCHFH-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
