Compound Q&A

How is 3-Bromo-N,N-bis(4-methylphenyl)aniline (CAS: 845526-91-2) typically synthesized?

Answer

3-Bromo-N,N-bis(4-methylphenyl)aniline
3-Bromo-N,N-bis(4-methylphenyl)aniline (CAS: 845526-91-2) is typically synthesized via a series of reactions starting from 4-methylphenyl aniline. The process involves bromination of the amino group followed by coupling with another 4-methylphenyl group. This can be achieved using NBS (N-bromosuccinimide) as the brominating agent and a suitable base like potassium carbonate in an organic solvent. The yield is moderate and the reaction is performed under mild conditions to ensure selectivity.

About

English Name 3-Bromo-N,N-bis(4-methylphenyl)aniline
Molecular Formula C20H18BrN
Molecular Weight 352.28 g/mol
SMILES CC1=CC=C(C=C1)N(C2=CC=C(C=C2)C)C3=CC(=CC=C3)Br
InChIKey LBLFZUNRAGUAFR-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53

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