Compound Q&A
How is 5-Iodo-3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one (CAS: 135352-71-5) typically synthesized?
Answer
![5-Iodo-3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one](https://static.chemtradehub.com/structs/135/135352-71-5-db1f.webp "5-Iodo-3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one")
5-Iodo-3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one is commonly synthesized through the iodination of 3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one using sodium iodide in the presence of an appropriate base such as sodium hydride. The reaction yields the desired product in good to excellent purity and selectivity.
About
CAS No
135352-71-5
English Name
5-Iodo-3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one
Molecular Formula
C6H4IN3O
Molecular Weight
261.02 g/mol
SMILES
C1=C(C2=C(N1)N=CNC2=O)I
InChIKey
QHYIUMOXLCMESH-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
![5-Iodo-3H-pyrrolo[2,3-D]pyrimidin-4(7H)-one — Leyan Reagents](https://static.chemtradehub.com/suppliers/67ce1f8657537e5c8069b370/67ce1f8657537e5c8069b370-logo.webp){kind=logo}