Compound Q&A
How is 5-{[5-(4-Fluorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione (CAS: 1218777-13-9) typically synthesized?
Answer
![5-{[5-(4-Fluorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione](https://static.chemtradehub.com/structs/121/1218777-13-9-5a60.webp "5-{[5-(4-Fluorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione")
5-{[5-(4-Fluorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione is synthesized using a multi-step process involving the condensation of 5-(4-fluorophenyl)furan-2-one with thiosemicarbazide. The reaction typically requires mild heating and a suitable solvent. The yield can be improved by using a catalyst, and the product is purified by recrystallization from ethanol.
About
CAS No
1218777-13-9
English Name
5-{[5-(4-Fluorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione
Molecular Formula
C14H8FNO3S
Molecular Weight
289.29 g/mol
SMILES
O=C1SC(=Cc2ccc(o2)c2ccc(cc2)F)C(=O)N1
InChIKey
UFBTYTGRUBUUIL-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33
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