Compound Q&A

How is 2-[(1R)-3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol hydrobromide (CAS: 837376-36-0) typically synthesized?

Answer

2-[(1R)-3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol hydrobromide (1:1)
2-[(1R)-3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol hydrobromide (CAS: 837376-36-0) is typically synthesized via the reaction of 4-methylphenol with 3-(diisopropylamino)-1-phenylpropyl bromide in the presence of a base like sodium hydride. The yield is generally high, and the reaction is selective and efficient. The product is isolated by recrystallization or column chromatography, and further purified through spectroscopic techniques.

About

English Name 2-[(1R)-3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol hydrobromide (1:1)
Molecular Formula C22H32BrNO
Molecular Weight 406.41 g/mol
SMILES CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2.Br
InChIKey ZMIOHGDJVPQTCH-VEIFNGETSA-N
Last Updated: 2025-10-31 17:33

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