Compound Q&A
How is Benzyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 315718-05-9) typically synthesized?
Answer
Benzyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 315718-05-9) can be synthesized via the condensation of benzyl chloroacetate with 1-hydroxypyrrolidine in the presence of an inorganic base such as potassium carbonate. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is usually around 75-85%, and the product can be isolated by column chromatography after purification.
About
CAS No
315718-05-9
English Name
Benzyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate
Molecular Formula
C13H17NO3
Molecular Weight
235.28 g/mol
SMILES
C1CN(CC1CO)C(=O)OCC2=CC=CC=C2
InChIKey
ZRMWRJLLAVAFQP-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33
