Compound Q&A

How is [2-(tert-butoxycarbonylamino)-3-pyridyl]boronic acid (CAS: 863753-35-9) typically synthesized?

Answer

[2-(tert-butoxycarbonylamino)-3-pyridyl]boronic acid
[2-(tert-Butoxycarbonylamino)-3-pyridyl]boronic acid (CAS: 863753-35-9) can be synthesized through the condensation of 2-amino-3-pyridineboronic acid with tert-butyloxycarbonyl chloride in the presence of a suitable base such as triethylamine. The reaction yields a mixture that can be purified by recrystallization or column chromatography, with a yield typically around 80-85%.

About

English Name [2-(tert-butoxycarbonylamino)-3-pyridyl]boronic acid
Molecular Formula C10H15BN2O4
Molecular Weight 238.05 g/mol
SMILES O=C(NC1=NC=CC=C1B(O)O)OC(C)(C)C
InChIKey QOAIOWWKQBFCQE-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33

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