[2-(tert-butoxycarbonylamino)-3-pyridyl]boronic acid(CAS: 863753-35-9)

[2-(tert-butoxycarbonylamino)-3-pyridyl]boronic acid (CAS: 863753-35-9) is a white crystalline solid with a molecular weight of approximately 304.35 g/mol. It is slightly soluble in water and ethanol. The compound has a moderate reactivity in boronate ester formation and other nucleophilic substitution reactions. It is stable under normal storage conditions but should be protected from moisture and air.

[2-(tert-Butoxycarbonylamino)-3-pyridyl]boronic acid (CAS: 863753-35-9) can be synthesized through the condensation of 2-amino-3-pyridineboronic acid with tert-butyloxycarbonyl chloride in the presence of a suitable base such as triethylamine. The reaction yields a mixture that can be purified by recrystallization or column chromatography, with a yield typically around 80-85%.

[2-(tert-Butoxycarbonylamino)-3-pyridyl]boronic acid (CAS: 863753-35-9) finds applications in pharmaceuticals for the synthesis of biologically active compounds, in polymers for modifying their properties, and in sensors for detection of various analytes. It is also used in the semiconductor industry for producing functionalized materials.

When handling [2-(tert-Butoxycarbonylamino)-3-pyridyl]boronic acid (CAS: 863753-35-9), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a dry place away from moisture and handled in a fume hood to avoid inhalation. In case of spill, it should be cleaned up carefully, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.