Compound Q&A

How is 4-fluorobenzene-1-carboximidamide (CAS: 2339-59-5) typically synthesized?

Answer

4-fluorobenzene-1-carboximidamide
4-Fluorobenzene-1-carboximidamide (CAS: 2339-59-5) can be synthesized through the acylation of 4-fluorobenzenesulfonamide with acyl halides in the presence of a base. This method provides high yield and good selectivity. Commonly used catalysts include sodium hydride and triethylamine. The reaction is typically carried out in anhydrous solvents such as dimethylformamide (DMF) or N,N-dimethylacetamide (DMAc) under mild conditions.

About

CAS No 2339-59-5
English Name 4-fluorobenzene-1-carboximidamide
Molecular Formula C7H7FN2
Molecular Weight 138.14 g/mol
SMILES C1=CC(=CC=C1C(=N)N)F
InChIKey OSTGTIZRQZOYAH-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33

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