Compound Q&A
How is Methyl 3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate (CAS: 79128-68-0) typically synthesized?
Answer
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Methyl 3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate is synthesized through a multi-step process involving the protection of a thiophene ring with trifluoroacetic anhydride, followed by amino substitution. The reaction is catalyzed by a strong base like sodium hydride, and the overall yield is around 75%.
About
CAS No
79128-68-0
English Name
Methyl 3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate
Molecular Formula
C8H6F3NO3S
Molecular Weight
253.201 g/mol
SMILES
COC(=O)C1=C(C=CS1)NC(=O)C(F)(F)F
InChIKey
CJNCTQZMIQZVQQ-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
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