Compound Q&A
How is 2-[(Trimethylsilyl)ethynyl]benzaldehyde (CAS: 77123-58-1) typically synthesized?
Answer
![2-[(Trimethylsilyl)ethynyl]benzaldehyde](https://static.chemtradehub.com/structs/771/77123-58-1-7122.webp "2-[(Trimethylsilyl)ethynyl]benzaldehyde")
2-[(Trimethylsilyl)ethynyl]benzaldehyde can be synthesized via Grignard reaction. The typical synthesis involves the reaction of phenylmagnesium bromide with ethynyltrimethylsilane. The process requires anhydrous conditions and is typically carried out in ether or THF. The yield is usually around 70-80%, and the product can be purified by recrystallization.
About
CAS No
77123-58-1
English Name
2-[(Trimethylsilyl)ethynyl]benzaldehyde
Molecular Formula
C12H14OSi
Molecular Weight
120.15 g/mol
SMILES
C[Si](C)(C)C#CC1=CC=CC=C1C=O
InChIKey
IROGCMISRBINQX-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
![2-[(Trimethylsilyl)ethynyl]benzaldehyde — Leyan Reagents](https://static.chemtradehub.com/suppliers/67ce1f8657537e5c8069b370/67ce1f8657537e5c8069b370-logo.webp){kind=logo}
![2-[(Trimethylsilyl)ethynyl]benzaldehyde — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![2-[(Trimethylsilyl)ethynyl]benzaldehyde — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![2-[(Trimethylsilyl)ethynyl]benzaldehyde — ShangHaiMaiRuiErShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67ced3b52b2de6e8e95a6e52/67ced3b52b2de6e8e95a6e52-logo.webp){kind=logo}